Randomized trial of two administration schedule of bonephos (Clodronate) in patients with painful bone metastasis |
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| Authors: | Moiseenko V M Blinov N N Semiglazov V V Konstantinova M M Trishkina E A |
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| Affiliation: | Prof. N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF. St. Petersburg. |
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| Abstract: | A randomized study of two intravenous schedules of Clodronate showed that a single 4-hour infusion of 1500 mg Clodronate proved significantly more effective than the traditional 2 hours infusion of 300 mg during 5 days. The regimen may prove preferable in therapy of patients with painful bone metastases. |
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