| 脂类过氧化与某些疾病 |
| |
| 引用本文： | 赖慕贤,陈一玲,陈志琼,陈耕夫,黎秀墀,梅克治.脂类过氧化与某些疾病[J].广东药学院学报,1989(1). |
| |
| 作者姓名： | 赖慕贤 陈一玲 陈志琼 陈耕夫 黎秀墀 梅克治 |
| |
| 作者单位： | 广东医药学院生物化学教研室，广东医药学院生物化学教研室，广东医药学院生物化学教研室，广东医药学院生物化学教研室，广州红十字会医院，广州红十字会医院 |
| |
| 摘 要： | 自由基损伤生物大分子,使脂类过氧化,造成膜损伤;机体抗氧化体系(维生素E,超氧化物歧化酶,谷胱甘肽过氧化物酶等)作用的削弱会加重自由基的细胞毒作用。本文测定了非胰岛素依赖型糖尿病、慢性肾炎和冠心病患者血清中丙二醛(MDA)、水溶性荧光物质(WSFS)和谷胱甘肽过氧化物酶(GSH-PX)水平,表明自由基损伤与该三种疾病相关。
|
| 关 键 词： | 自由基 脂类过氧化 糖尿病 冠心病 慢性肾炎 |
LIPID PEROXIDATION AND SOME DISEASES |
| |
| Lai Muxian.LIPID PEROXIDATION AND SOME DISEASES[J].Academic Journal of Guangdong College of Pharmacy,1989(1). |
| |
| Authors: | Lai Muxian |
| |
| Institution: | Lai Muxian Department of Biochemistry Guangdong Medical and pharmaceutical college |
| |
| Abstract: | Free radical hurts biological large molecules, lets lipid peroxid- ize and damages membrane, the weakening of antiperoxidation system in vivo (vit E, SOD, GSH-PX) will increase the harmful effect of radical on cells. We examined the MDA, WSFS and GSH-PX level in serum of patients suffered from non-insulin dependent diabetes, chronic nephritis and coronary heart disease. The result indicates that the damage of free radical relates to these three diseases. |
| |
| Keywords: | free radical lipid peroxidation diabetes coronary heart disease chronic nephritis |
| 本文献已被 CNKI 等数据库收录！ |
|
