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体外循环对机体免疫功能的影响
引用本文:阎恒宇,耿树刚,谷春久. 体外循环对机体免疫功能的影响[J]. 中国冶金工业医学杂志, 2003, 20(1): 9-10
作者姓名:阎恒宇  耿树刚  谷春久
作者单位:1. 鞍钢铁东医院心脏外科,辽宁鞍山,114002
2. 中国医科大学第一临床学院
摘    要:目的:探讨体外循环对机体免疫 功能的影响。方法:测定体外循环组与非体外循环组术前、术后第1天、第4天、第7天血中IgA、IgM、IgG以及NK活性、IL-2、IFN-r 的变化。结果:体外循环术后上述各项指标水平降低,降低程度与体外循环时间长短有关。结论:体外循环降低了机体免疫力,体外循环时间越长免疫损害越重。

关 键 词:体外循环 免疫功能 循环时间
文章编号:1005-5495(2003)01-0009-02

Influence of cardiopulmonary bypass on immune function of organism
Yan Hengyu ,Geng Shugang ,Gu Chunjiu. Influence of cardiopulmonary bypass on immune function of organism[J]. Chinese Medical Journal of Metallurgical Industry, 2003, 20(1): 9-10
Authors:Yan Hengyu   Geng Shugang   Gu Chunjiu
Affiliation:Yan Hengyu 1,Geng Shugang 1,Gu Chunjiu 2.Department of Cardiac Surgery,Tiedong Hospital of Anshan Iron and Steel Company 1.Anshan 114002.The First Affiliated of Hospital of China Medical University 2.
Abstract:Objective:To investigate the influence of cardiopulmonary bypass on immune function of organism.Methods:The activity of IgA?IgM?IgG.NK and the changes of IL-2?IFN-r in blood at preoperation and 1?4?7 days postoperation in the CPB group and the control group were detected respectively.Results:The level of these markers postoperation in the CPB group decreased,and the degree of decrease was related to the length of the time of CPB.Conclusions:The CPB could decrease the immune function of organism,the longer time of CPB,the more serious damage of the immune function of organism.
Keywords:Cardiopulmonary bypass Immune function
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