| 比色法测定罗红霉素氨溴索干混悬剂的溶出度 |
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| 引用本文： | 孙峰,姚宏涛. 比色法测定罗红霉素氨溴索干混悬剂的溶出度[J]. 中国药品标准, 2009, 10(3): 225-228 |
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| 作者姓名： | 孙峰 姚宏涛 |
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| 作者单位： | 1. 沈阳东陵药业股份有限公司,沈阳,110161
2. 沈阳市山日药物研究所,沈阳,110015 |
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| 摘 要： | 目的:建立罗红霉素氨溴索干混悬剂的溶出度测定方法.方法:采用比色法测定罗红霉素氨溴索干混悬剂的溶出量.结果:罗红霉素在60～100 mg·L-1的浓度范围内峰线性关系良好(R2=0.999 9),平均回收率在99.41%(n=9).结论:该方法准确可靠,简单快速,可用于罗红霉素氨溴索干混悬剂的溶出度的测定.
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| 关 键 词： | 罗红霉素氨溴索千混悬剂 溶出试验 比色法 |
Dissolution Test of Roxithromycin and Ambroxol Hydrochloride for Oral Suspension by Colorimetric Method |
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| Sun Feng and Yao Hong-tao. Dissolution Test of Roxithromycin and Ambroxol Hydrochloride for Oral Suspension by Colorimetric Method[J]. , 2009, 10(3): 225-228 |
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| Authors: | Sun Feng and Yao Hong-tao |
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| Affiliation: | Shenyang Dongling pharmaceutical Co., LTD, Shenyang 110161;Shenyang ShanRi Pharmacy Research Institute, Shenyang 110015 |
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| Abstract: | Objective: To establish a colorimetric method for dissolution Test of Ambroxol Hydrochloride for Oral Suspension.Methods: A colorimetric method was used in the dissolution Test.Results: The linear range for Roxithromycin was 60~100 mg·L-1(R2=0.999 9),the average recovery of Roxithromycin was 99.41%(n=9).Conclusion: A simple,rapid and accurate method for dissolution Test of Roxithromycin and Ambroxol Hydrochloride for Oral Suspension is established. |
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| Keywords: | Ambroxol Hydrochloride for Oral Suspension Dissolution test Colorimetric method |
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