| 对多器官功能障碍综合征肠源性机制的新认识 |
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| 引用本文： | 曹丽萍,邓诗琳. 对多器官功能障碍综合征肠源性机制的新认识[J]. 中华烧伤杂志, 2007, 23(4): 241-243 |
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| 作者姓名： | 曹丽萍 邓诗琳 |
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| 作者单位： | 1. 300121,天津市人民医院烧伤科
2. 天津市第四医院烧伤科 |
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| 摘 要： | 纵观当前对创（烧）伤后多器官功能障碍综合征（MODS）肠源性发病机制的研究，其发生发展可分为3个环节：（1）严重创伤后肠道缺血再灌注损伤，致肠道屏障功能受损发生MODS。（2）损伤肠道产生的肠源性毒性因子、肠道内细菌和内毒素通过血液循环及肠道淋巴途径，引起全身炎性反应综合征。（3）失控性炎性反应导致不可逆器官功能障碍，此环节是MODS发病机制中的最终环节[第一段]
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| 关 键 词： | 烧伤 多器官功能衰竭 肠系膜 淋巴 创伤 |
| 修稿时间： | 2007-02-23 |
Progress in gut-derived mechanism of multiple organ dysfunction syndrome after burns and trauma |
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| CAO Li-ping,DENG Shi-lin. Progress in gut-derived mechanism of multiple organ dysfunction syndrome after burns and trauma[J]. Chinese journal of burns, 2007, 23(4): 241-243 |
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| Authors: | CAO Li-ping DENG Shi-lin |
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| Affiliation: | Tianjin Union Medicine Centre , Tianjin 300121 ,P. R. China |
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| Abstract: | Multiple organ dysfunction syndrome (MODS) is a serious complication with higher mortality in patients with burns and trauma. It is important to study the mechanism of MODS for prevention and control of it. Mesenteric lymph mechanism of MODS is a new viewpoint of gut-derived mechanism of MODS in recent years. In this review, we elucidate the mechanism of gut-derived origin of MODS and role of mesenteric lymph path in development of MODS after burns and trauma injury. |
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| Keywords: | Burns Multiple organ dysfunction syndrome Mesenterium Lymph Trauma |
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