祖细胞和干细胞与缺血性疾病的治疗

缺血性疾病是严重危害人类健康的疾病之一,主要包括缺血性脑血管疾病、缺血性心血管疾病、下肢缺血性疾病等。祖细胞和干细胞都是具有自我复制能力的多潜能细胞,在一定条件下,它们可以分化成多种功能细胞。根据干细胞所处的发育阶段分为胚胎干细胞和成体干细胞,虽然胚胎干细胞具有万能分化型功能,但伦理学方面的争议使其研究困难重重,而成体干细胞相较胚胎干细胞,不仅避免了伦理学方面的争议问题,而且无移植后免疫排斥反应。本文主要讨论成体干细胞和祖细胞在缺血性疾病中的应用。近年来,关于祖细胞和干细胞在缺血性疾病中应用的研究日益增多,受到了广泛的关注,为我们提供了一条治疗缺血性疾病的新思路。

Progenitor cells and stem cells in the treatment of ischemic disease

Ischemic disease is one of the serious diseases that is harm to human health, which mainly includes ischemic cerebrovascular disease, ischemic heart disease, ischemic disease of lower extremities. Progenitor cells and stem cells are pluripotent cells with self-replicating ability. Under certain conditions, they are able to differentiate into a variety of cells. According to the developmental stages of stem cells, it is classified into embryonic stem cells and somatic stem cells. Although embryonic stem cells have abilities of differentiating into any cell, the ethics dispute makes its study difficult. Compared with embryonic stem cells, somatic stem cells can not only avoid the ethical controversy, but also have no immune rejection after transplanting. Therefore, this essay focuses on the application of stem cells and progenitor cells in ischemic disease. In recent years, the research on the application of progenitor cells and stem cells in this kind of disease has increased, and aroused wide attention, which provides us with a new approach to the treatment of ischemic diseases.