糖尿病与睡眠呼吸暂停及血压的关系

目的 探讨糖尿病与睡眠呼吸暂停及血压的相互关系及临床意义。方法 对20例Ⅱ型糖尿病（NIDDM）患和15例阻塞性睡眠呼吸暂停综合征（OSAS）患及18例正常人的多导睡眠图（PSG）结果进行对比研究。结果 糖尿病患有48%合并睡眠呼吸暂停（SA），且心脑血管并发症明显增多。糖尿病易引起睡眠期血压升高，睡眠呼吸暂停则是血压改变的促进因素。糖尿病在夜间的血压增高与血压财节功能失调及夜间缺氧所致血压的改变有关。结论 糖尿病与睡眠暂停及血压相互影响，此点对糖尿病防治有重要意义。

Correlation between diabetes, sleep apnea and blood pressure

AIM To study the correlation between diabetes, sleep apnea and blood pressure. METHODS The results of polysomnography (PSG) in 20 non insulin dependent diabetes mellitus (DM) patients were analyzed and compared with those of 15 obstructive sleep apnea syndrome (OSAS) patients and 18 healthy controls. RESULTS 48% of the DM patients were complicated by sleep apnea (SA). Complication of hypertension and cardio cerebral vascular diseases increased markedly ( P <0.01) in this group. DM could induce hypertension during sleep and SA was a facilitating factor in the change of blood pressure. CONCLUSION DM may cause sleep related breath disorders (SRBD) and is thought to be induced by naso pharyngeal muscular relaxation as a result of microangiopathy and neuro pathy of these muscles. A nocturnal hypertension occurs in DM and is suggested to be caused by the sympathetic hypertonia induced by autonomic dysfunction resulted from sleep apnea.