| 纳络酮对铝中毒小鼠学习记忆障碍的改善作用 |
| |
| 引用本文： | 顾饶胜,都培双,任旷,沈楠,梅丹,吴晓东,李平,何玲. 纳络酮对铝中毒小鼠学习记忆障碍的改善作用[J]. 临床军医杂志, 1999, 0(1) |
| |
| 作者姓名： | 顾饶胜 都培双 任旷 沈楠 梅丹 吴晓东 李平 何玲 |
| |
| 作者单位： | 吉林市空军医高专!132013 |
| |
| 摘 要： | 在口服氯化铝导致学习记忆障碍模型的基础上，用跳台、避暗等实验方法观察了纳络酮对铝中毒小鼠学习记忆障碍的改善作用，并测定了肝丙二醇、脑B型单胺氧化酶的变化。实验结果显示，氯化铝可导致小鼠学习记忆障碍，以及增高丙二醛和B型单胶氧化酶的作用，而纳络酮对改善铝中毒小鼠学习记忆障碍有作用，同时有清除过氧化脂质和抑制B型单胶氧化酶活性的作用。
|
| 关 键 词： | 老年性痴呆 记忆力 纳络酮 铝 |
Improvement of Naloxone on the Learning and Memory Impairment Induced by Aluminium in Mice |
| |
| Gu Raosheng,et al. Improvement of Naloxone on the Learning and Memory Impairment Induced by Aluminium in Mice[J]. Clinical Journal of Medical Officer, 1999, 0(1) |
| |
| Authors: | Gu Raosheng et al |
| |
| Affiliation: | 132013 Ji lin Air Force Junior College of Medicine |
| |
| Abstract: | The effects 0f naloxone on the learning and mem0ry impairment induced by aluminium chloride was studied by means of step down test and step through test. Thq contentof the MDA and MAO-B was also observed. The results showed that aluminium chloridecould induced lear ning and memory impairment in mice. Wile naloxone could improve the impairment of the learning and memory. |
| |
| Keywords: | senile dementia memory naloxone aluminium |
| 本文献已被 CNKI 等数据库收录！ |
