低分子肝素联合硫酸镁治疗妊娠期高血压综合征的临床观察

目的探讨低分子肝素治疗妊娠期高血压综合征中的疗效及其安全性。方法40例纳入患者随机分为两组。治疗组20例，采用低分子肝素联合硫酸镁治疗；对照组20例，采用硫酸镁治疗。3d为1个疗程。结果治疗组血压、D一二聚体较对照组明显降低（P〈0．05）；两组血小板计数、凝血酶原时问和出血情况无明显差异（P〉0．05）。结论低分子肝素治疗妊娠期高血压综合征重度子痫前期疗效确切，安全可靠，值得推广应用。

Clinical observation of low molecular weight heparin combined with magnesium sulfate treatment on patients with pregnancy-induced hypertension

Objective To observe the clinical effect and safety of low molecular weight heparin in treatment of pregnancy-induced hypertension. Methods 40 patients included were randomly divided into two groups. 20 patients of treatment group were treated with low molecular weight heparin combined with magnesium sulfate. 20 patients of control group were treated with magnesium sulfate. Results The blood pressure and D-dimer of treatment group were significantly lower than control group ( P ＜ 0. 05 ). The platelet count, prothrombin time and bleeding of two groups were not significant different ( P ＞ 0. 05 ). Conclusion Low molecular weight heparin used in the treatment of severe pre-eclampsia pregnancy-induced hypertension are effeclive,safe and reliable, worthy of popularization.