老年慢性阻塞性肺疾病患者营养状况与肺通气量的关系

目的研究慢陛阻塞性肺疾病（chronic obstructive pulmonary disease, COPD）患者营养状况与肺通气功能的关系。方法对217例患者进行以身体组成评价法（BCA）营养状况调查。根据其营养评价结果分为营养良好组和营养不良组，两组进行肺通气功能测定，观察指标包括：最大通气量（MVV），用力肺活量（FVC），第1秒用力呼气容积（FEV1），最大呼气流量（PEF）。结果在调查的217例患者中，有67例患者营养状况良好，占30．87％，有150例COPD患者被评为营养不良，营养不良发生率为69．13％。营养不良组的肺通气量指标MVV％（36．21±17．36）、FVC％（75．42±19．65）、FEV1％（41．92±16．29）、PEF％（36．06±17．25）均低于营养良好组MVV％（59．25±22．61）、FVC％（93．19±15．32）、FEV1％（52．3±14．43）、PEF％（68．19±24．23），差异有统计学意义（P〈0．05）。结论COPD患者的营养状况评价结果均不理想，而营养不良会使呼吸肌储备力量下降及呼吸肌容易疲劳，导致肺通气功能降低，所以改善COPD患者营养不良的发生，对肺通气功能恢复有重要意义。

Study on correlation between nutritional status and pulmonary ventilation in patients with chronic obstructivepulmonary disease

Objective To study the correlation between nutritional status and pulmonary function in patients with chronic obstructive pulmonary disease （COPD）. Method A total of 217 COPD patients were divided into well-nourished group and malnutrition group based on their Body Composition Assessment （BCA） nutrition survey results. Pulmonary function were measured including maximal voluntary ventilation （MVV）, forced vital capacity （FVC）, forced expiratory volume in one second （FEV0 and peak expiratory flow （PEF）. Results Among the 217 patients, 67 were in good nutrition, accounting for 30.87%; 150 were rated as malnutrition, malnutrition rate was 69.13%. MVV% （36.21±17.36）, FVC % （75.42±19.65）, FEV1% （41.92± 16.29） and PEF% （36.06±17.25） of the malnutrition group were significantly lower thanMVV% （59.25±22.61）, FVC% （93.19±15.32）, FEV1% （52.3±14.43）andPEF% （68.19±24.23）of those in good nutrition （P 〈 0.05 ）. Conclusion Nutrition status of COPD patients are not good, malnutrition can cause respiratory muscle reserve strength decline and respiratory muscle fatigue, which could lead to the decrease of pulmonary ventilation function. Improve the nutrition of COPD patients is of great importance to the recovery of pulmonary ventilation function.