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人巴贝虫病研究进展
引用本文:蒋明,张仪. 人巴贝虫病研究进展[J]. 国际医学寄生虫病杂志, 2014, 41(2): 94-98,104
作者姓名:蒋明  张仪
作者单位:蒋明 (200025上海,中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾、血吸虫病和丝虫病合作中心); 张仪 (200025上海,中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾、血吸虫病和丝虫病合作中心);
基金项目:卫生行业科研专项(项目编号:201202019)国家重大科技专项(项目编号:2012ZX10004220)the,Special,Fund,for,Health,Research,in,Public,Interest(项目编号:201202019)National,Scienceand,Technology,Major,Program(项目编号:2012ZX10004220)
摘    要:巴贝虫病是巴贝虫在红细胞内寄生导致的一种人畜共患寄生虫病.人巴贝虫病主要由田鼠巴贝虫(Babesia microti)、B.duncani、分歧巴贝虫(B.divergens)、B.venatorum等引起,病例呈世界性分布.其传播方式有蜱虫叮咬、输血及母婴传播等.患病症状与疟疾相似,典型的临床症状表现为发热、肌痛、贫血、血红蛋白尿、黄疸等,其严重程度主要取决于自身免疫状况和感染巴贝虫的种类.巴贝虫病常见的诊断方法为涂片染色法、动物接种法、血清学检测法以及分子生物学检测法.

关 键 词:巴贝虫病  输血传播巴贝虫病  流行状况  诊断方法  预防控制

Research progress on human babesiosis
Jiang Ming,Zhang Yi. Research progress on human babesiosis[J]. International JOurnal of Medical Parasitic Diseases, 2014, 41(2): 94-98,104
Authors:Jiang Ming  Zhang Yi
Affiliation:. National( Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, Ministry of Health, WHO Collaborating Center for Malaria, Schistosomiosisand Filariosis, Shanghai 200025, China)
Abstract:Babesiosis, caused by infection with intraerythrocytic parasites of the genus Babesia,is an emerging zoonosis in human. The major species involved in human cases are Babesiamicroti,B. duncani, B. divergens ,B. venatorum. The three infection routes in human are tick biting, blood transfusion and vertical transmission. Clinical manifestations of babesiosis are similar to acute malaria, including fever, malaise, anemia, hemoglobinuria and jaundice. The severity of babesiosis depends primarily on the immune status of the patient and Babesia species. The major diagnostic techniques of babesiosis include Giemsa-stained exami- nation of thin blood smears, inoculation of susceptible animals with whole blood, serodiagnostic test and DNA amplification by PCR.
Keywords:Babesiosis  Transfusion-transmitted babesiosis  Epidemiology  Diognosis  Prevention
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