| ghrelin抗炎作用机制的研究进展 |
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| 引用本文： | 谢秀芳.ghrelin抗炎作用机制的研究进展[J].国际呼吸杂志,2014,34(2):111-114. |
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| 作者姓名： | 谢秀芳 |
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| 作者单位： | 谢秀芳 (泸州医学院附属医院呼吸二科,646000)； |
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| 摘 要： | 生长素释放肽（ghrelin）参与了调节垂体生长激素的释放、调节能量代谢、保护心血管、调节炎症反应等多种生物学功能，其中抗炎作用机制与免疫调节、植物神经功能、晚期重要炎症因子高迁移率蛋白B1、核因子κB及核苷酸结合寡聚域2／受体相互作用蛋白2等信号传导通路有关。本文就近年来ghrelin在炎症反应中的作用机制研究进行综述。
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| 关 键 词： | 生长素释放肽 炎症反应 核因子κB 核苷酸结合寡聚域2 受体相互作用蛋白2 |
Research progress on anti-inflammatory mechanism of ghrelin |
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| Xie Xiufang.Research progress on anti-inflammatory mechanism of ghrelin[J].International Journal of Respiration,2014,34(2):111-114. |
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| Authors: | Xie Xiufang |
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| Institution: | Xie Xiufang. Department of Respiratory Medicine ,Affiliated Hospital of Luzhou Medical College ,Luzhou 646000 ,China |
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| Abstract: | Growth hormone releasing pepride （ghrelin） is participated in many kinds of biological function, including the adjustion of pituitary growth hormone, energy metabolism, cardiovascular protective effection, anti-inflammatory response and so on. The mechanism of anti-inflammatory is related with immune adjustment,plant nerve function adjustment, late important inflammatory factor mobility of high protein B1, multiple signaling pathways such as nuclear factor-κB, nucleotide binding oligomeric domain 2/receptor interacting protein 2. The mechanism of ghrelin in the inflammatory reaction is summarized in this paper. |
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| Keywords: | Ghrelin Inflammatory action Nuclear factor-κB Nucleotide binding oligomeric domain 2/receptor interacting protein 2 |
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