高通量透析对急性肾功能不全患者生存率及康复率的影响

目的通过对各个临床试验数据的综合分析,对不同透析膜对肾衰竭患者的临床疗效作一评价。方法将普通纤维素透析膜与高通量透析膜对急性肾功能不全患者的治疗结果进行比较,综合其数据进行Meta分析。结果在入选的8份临床对照研究文献中,有7篇的结果表明,与低通量透析相比,高通量透析可以有效提高急性肾功能不全患者的生存率,其OR为1．56,95％置信区间为（1．15,2．13）,P=0．005。而对于康复率而言,两种透析则无显著差异。结论应用高通量透析膜进行血液透析,可以有效改善急性肾功能不全患者的生活质量,提高其生存率。

Effect Analysis of High-Flux Hemodialysis to Survival and Recovery Rate of Patients with Acute Renal Failure

Objective To evaluate the clinical effect of different dialysis membranes for patients with acute renal failure by a comprehensive analysis of the clinical trial data. Methods The curative effects of low-flux dialysis membrane and high-flux dialysis membrane for patients with acute renal failure were compared, and the related data were taken for Meta-analysis. Results The cumulative OR for survival in favor of high-flux membrance was 1.56, and CI was 1.15 to 2.13. The Pvalue was 0.005, with no statistical difference between two methods in the recovery rate. Conclusions High-flux dialysis membrane used for hemodialysis can effectively improve quality of life for patient with acute renal failure, and improve the patient＇s survival rate.