| 慢性阻塞性肺疾病时血清脂类过氧化产物和微量元素水平的研究 |
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| 引用本文： | 钟献年,梅月华,陈一玲,叶焕群,林健濂. 慢性阻塞性肺疾病时血清脂类过氧化产物和微量元素水平的研究[J]. 广东药学院学报, 1988, 0(2) |
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| 作者姓名： | 钟献年 梅月华 陈一玲 叶焕群 林健濂 |
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| 作者单位： | 广东医药学院广东医药学院内科学教研室，广东医药学院广东医药学院内科学教研室，广东医药学院生物化学教研室，广东医药学院广州市红十字会医院内科，广东医药学院广州市红十字会医院内科 |
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| 摘 要： | 本文研究慢性阻塞性肺病(COPD)患者血清脂类过氧化产物、抗过氧化酶类和微量元素(锌、铜、铁)的含量。检测COPD患者30人,并将结果与30个正常人进行对比,其结果表明:COPD患者体内脂类过氧化产物增多而抗氧化酶类水平降低以及微量元素的比例失调(铜高而锌、铁低于正常人)。本研究对于临床探讨应用抗氧化剂和微量元素治疗疾病有重要的实用价值。
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| 关 键 词： | 丙二醛 水溶性荧光物质 谷胱甘肽过氧化物酶 微量元素 |
STUDIES ON SERUM LEVELS OF PRODUCTS OF LIPID PEROXIDATION AND TRACE ELEMENT IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE(COPD) |
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| Zhong XianNian. STUDIES ON SERUM LEVELS OF PRODUCTS OF LIPID PEROXIDATION AND TRACE ELEMENT IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE(COPD)[J]. Academic Journal of Guangdong College of Pharmacy, 1988, 0(2) |
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| Authors: | Zhong XianNian |
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| Affiliation: | Zhong XianNian Department of Internal Medicine Guangdong Medical and Pharmaceutical college |
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| Abstract: | The products of lipid peroxidation, activity of antiperoxidase and trace elements in serum were studied in 30 patients with COPD and these results were compared with 30 normal controls. The resulst showed that there were increase in lipid peroxidation product (WSFS), decrea- se in activity of antiperoxidase (GSH-PX) and that the rate of trace ele- ment were unbalance in patients with COPD (Cu was higher and Fe and Zn were lower than normal controls P<0.05). There are Practical Value for treatment of COPD with antiperoxidation and trace elements. |
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| Keywords: | Malondialdehyde(MDA)Water-soluble fluorescent substances(WSFS) Glutathione peroxidase(GSH-PX)Trace elements. |
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