Kikuchi-Fujimoto disease associated with mixed connective tissue disease |
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Authors: | Pallet N Aaron L Larousserie F Therby A Dupont B Viard J-P |
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Affiliation: | Department of Infectious and Tropical Diseases, Hopital Necker-Enfants Malades, Paris, France. |
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Abstract: | Kikuchi-Fujimoto disease is characterized by painful cervical lymphadenopathy and constitutional symptoms. Microscopical study of lymph nodes shows focal areas of non-suppurative necrosis with histiocytic and plasmacytoid cell infiltrates. The course is usually benign. Often primitive, necrotising histiocytic lymphadenopathy may be associated with autoimmune disorders. We describe the case of a 30-year-old female patient with two 15-day courses of Kikuchi-Fujimoto disease flares within a period of 3 months, occurring in association with mixed connective tissue disease. |
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