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垂体腺瘤的X刀治疗
引用本文:闫志钧,林志国,沈红,李庆国,隋立森,浦松.垂体腺瘤的X刀治疗[J].立体定向和功能性神经外科杂志,2001,14(4):220-222.
作者姓名:闫志钧  林志国  沈红  李庆国  隋立森  浦松
作者单位:哈尔滨医科大学第一临床医院X刀、立体定向神经外科,
摘    要:目的:观察分析X刀对垂体瘤的治疗效果。方法:对1997年1月至2000年6月应用Radionic公司头部X刀系统,治疗的垂体腺瘤患者随访54例,单次治疗32例,分次治疗22例。其中54例获得影像学复查,36例获得血激素水平复查。随访期3个月到32个月,平均13.2个月。结果:肿瘤缩小达55.6%,无一例肿瘤增大;临床症状改善率72.2%,随访期3个月到32个月,平均13.2个月。结果:肿瘤缩小达55.6%,无一例肿瘤增大;临床症状改善率72.2%,无临床症状加重着。血激素水平恢复正常达30.6%。结论:X刀治疗垂体腺瘤安全、有效、无明显副作用,SRT治疗后血激素水平恢复正常率高于SRS治疗,但血激素水平恢复时间长于SRS治疗。

关 键 词:垂体腺瘤  X-刀  单次治疗  分次治疗
修稿时间:2001年6月25日

Initial clinical results of stereotactic radiosurgery and stereotactic radiotherapy for pituitary ad- enomas
Lin Zhiguo,Yan Zhijun,Shen Hong,et al..Initial clinical results of stereotactic radiosurgery and stereotactic radiotherapy for pituitary ad- enomas[J].Chinese Journal of Stereotactic and Functional Neurosurgery,2001,14(4):220-222.
Authors:Lin Zhiguo  Yan Zhijun  Shen Hong  
Institution:Lin Zhiguo,Yan Zhijun,Shen Hong,et al. x - knife center and Stereotactic Neurosurgical Department,The First Affiliated Hospital,Harbin Medical University,Harbin 150001
Abstract:Objective: To evaluate the initial results of stereotactic radiosurgery (SRS) and frac- tionated stereotactic radiotherapy(SRT) pituitary adenomas with regard to tumor and hormonal con- trol. Methods: 54 patients with pituitary adenomas who nuderwent SRS or SRT between January 1997 and June 2000 reciowere follow - up survey. Of these, 54 patients received CT of MRI reexamination. 36 patients received blood hormone reexamination. These patients were follow - up from 3 months to 32 months. Mean time was 13. 2 months. Results: The percentage of pituitary adenomas shrink was 55. 6 %. there was no tumor geowth. The remission rate of clinical sympton was 72. 2 %. The recovery rate of blood hormone was 30. 6 %. Conclusion: X - knife is valuable for treatment of pituitary adeno- mas and it is well tolerated therapy. The recovery rate of blood hormone were more effective SRT than SRS. The time of hormone rcivery were longer in SRT than SRS.
Keywords:Pituitary adenomas  X - knife  SRS  SRT
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