| 胃癌行腹主动脉旁淋巴结清扫的研究进展 |
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| 引用本文： | 于鹏程,徐志远,王以,胡灿,程向东. 胃癌行腹主动脉旁淋巴结清扫的研究进展[J]. 中国肿瘤临床, 2022, 49(17): 903-907. DOI: 10.12354/j.issn.1000-8179.2022.20211954 |
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| 作者姓名： | 于鹏程 徐志远 王以 胡灿 程向东 |
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| 作者单位： | 1.浙江中医药大学第一临床医学院（杭州市310053） |
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| 基金项目： | 本文课题受国家自然科学基金（编号:81973634）、浙江省上消化道肿瘤诊治技术研究中心（编号:JBZX-202006）和浙江省中医药科技计划重点项目（编号:2019ZZ010）资助 |
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| 摘 要： | 手术治疗是治疗胃癌的主要方式之一，标准的术中淋巴结清扫尤为重要。关于胃癌患者是否行腹主动脉旁淋巴结清扫（para-aortic lymph node dissection，PAND）仍存在争议。预防性PAND的意义被否定，但治疗性PAND的效果还有待进一步的研究去证实。术前化疗联合规范的手术治疗可能是未来进展期胃癌伴腹主动脉旁淋巴结转移的标准治疗模式。本文就胃癌行PAND的研究进行综述，以期为临床实践提供指导。
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| 关 键 词： | 腹主动脉旁淋巴结清扫 新辅助化疗 胃癌 |
| 收稿时间： | 2021-12-25 |
Research progress of para-aortic lymph node dissection for gastric cancer |
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| Affiliation: | 1.The First Clinical Medical College, Zhejiang Chinese Medicine University, Hangzhou 310053, China2.Department of Gastroenterology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou 310022, China3.Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou 310018, China4.The Second Clinical Medical College, Zhejiang Chinese Medicine University, Hangzhou 310053, China |
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| Abstract: | Surgery is one of the main ways to treat gastric cancer, and standard intraoperative lymph node dissection is particularly important. However, performing para-aortic lymph node dissection (PAND) in patients with gastric cancer is still controversial. The significance of preventive PAND has been denied. But further research is needed to confirm the effectiveness of therapeutic PAND. Preoperative chemotherapy combined with surgery may be the standard treatment strategy for advanced gastric cancer with para-aortic lymph node metastasis in the future. This article reviews the studies of PAND for gastric cancer to provide guidance for clinical practice. |
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