侵袭性血管黏液瘤研究进展

侵袭性血管黏液瘤（aggressive angiomyxoma，AA）是一种少见的、通常发生在生育期女性外阴和盆腔等部位的间叶源性肿瘤。虽然具有局部浸润和局部复发的生物学行为特点，但目前的观点认为其并非恶性肿瘤。2003年第3版和2013年第4版世界卫生组织（WHO）肿瘤分类将其纳入骨和软组织肿瘤类别，并将其划入分化不确定的肿瘤类型。迄今为止国内外报道的AA病例数已超过350例，这些报道均以病例报告并文献复习的形式为主。本文将结合最新文献就AA的研究进展进行综述。 

Research progress on aggressive angiomyxoma

Aggressive angiomyxoma (AA) is a rare mesenchymal tumor that generally occurs in the perineum and pelvis of women of reproductive age. Despite its characteristics of local infiltration and recurrence, it is not considered as a malignant tumor. The third (2003) and fourth (2013) editions of the World Health Organization Classification of Bone and Soft Tissue tumors classified it as a tumor of uncertain differentiation and named it "aggressive (deep) angiomyxoma." So far, more than 350 cases of aggressive angiomyxoma have been reported worldwide, mostly in the form of case reports and literature reviews. In this review, we present updated knowledge on AA.