| 基因、体力活动及其交互作用与2型糖尿病 |
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| 引用本文： | 梁军,邹彩艳,祁禄. 基因、体力活动及其交互作用与2型糖尿病[J]. 国际内分泌代谢杂志, 2010, 30(1). DOI: 10.3760/cma.j.issn.1673-4157.2010.01.017 |
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| 作者姓名： | 梁军 邹彩艳 祁禄 |
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| 作者单位： | 东南大学医学院附属徐州医院内分泌科,徐州市中心医院,221009;美国哈佛大学公共卫生学院营养学及流行病学系,021150 |
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| 摘 要： | 2型糖尿病是目前威胁人类健康,发病率迅速增长的疾病之一.2007年以来,全基因组关联分析研究发现一系列包括SLC30A8、LOC387761、IDE-KIF11-HHEX和EXT2-ALX4等新的糖尿病基因.基因及体力活动不足与2型糖尿病患病风险相关,且两个因素可能有交互影响,本文就基因、体力活动及其交互作用与2型糖尿病间的关系作一综述.
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| 关 键 词： | 基因 体力活动 交互作用 2型糖尿病 预防 |
Relationship of genes,physical activity and their interactions and type 2 diabetes |
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| LIANG Jun,ZOU Cai-yan,QI Lu. Relationship of genes,physical activity and their interactions and type 2 diabetes[J]. International JOurnal of Endocrinology and Metabolism, 2010, 30(1). DOI: 10.3760/cma.j.issn.1673-4157.2010.01.017 |
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| Authors: | LIANG Jun ZOU Cai-yan QI Lu |
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| Abstract: | Type 2 diabetes is one of the fastest growing public health problems worldwide.Since 2007,genome-wide association study (GWAS) emerged to generate a list of new diabetes genes including SLC3OA8,LOC387761,IDE-KIF11-HHEX,EXT2-ALX4 and so on.Studies show that genes and physical inactivity are leading to type 2 diabetes,the two factors may interplay in predisposing to the disease.Relationship of genes,physical activity and their interactions and type 2 diabetes were discussed. |
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| Keywords: | Gene Physical activity Interactions Type 2 diabetes mellitus Prevention |
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