| A STUDY ON DETECTION OF SERUM FASTING TOTAL BILE ACID AND CHOLOYGLYCIN IN NEONATE FOR CHOLESTASIS |
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| 引用本文： | 郭文,吴明昌,裴学义,关德华,徐洛.A STUDY ON DETECTION OF SERUM FASTING TOTAL BILE ACID AND CHOLOYGLYCIN IN NEONATE FOR CHOLESTASIS[J].中国医学科学杂志,1996(4). |
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| 作者姓名： | 郭文 吴明昌 裴学义 关德华 徐洛 |
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| 作者单位： | Beijing Children Hospital，Beijing 100045 |
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| 摘 要： | ＡＳＴＵＤＹＯＮＤＥＴＥＣＴＩＯＮＯＦＳＥＲＵＭＦＡＳＴＩＮＧＴＯＴＡＬＢＩＬＥＡＣＩＤＡＮＤＣＨＯＬＯＹＧＬＹＣＩＮＩＮＮＥＯＮＡＴＥＦＯＲＣＨＯＬＥＳＴＡＳＩＳＧｕｏＷｅｎ（郭文）；ＷｕＭｉｎｇｃｈａｎｇ（吴明昌）；ＰｅｉＸｕｅｙｉ（裴学义）；Ｇ...
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A STUDY ON DETECTION OF SERUM FASTING TOTAL BILE ACID AND CHOLOYGLYCIN IN NEONATE FOR CHOLESTASIS |
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| Guo Wen, Wu Mingchang,Pei Xueyi, Guan Dehua and Xu Luo.A STUDY ON DETECTION OF SERUM FASTING TOTAL BILE ACID AND CHOLOYGLYCIN IN NEONATE FOR CHOLESTASIS[J].Chinese Medical Sciences Journal,1996(4). |
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| Authors: | Guo Wen Wu Mingchang Pei Xueyi Guan Dehua and Xu Luo |
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| Abstract: | Enzyme-linked colorimetric analysis and adioimmunoassay were employed to detect serum fasting total bile acids(FBA) and choloyglycin (CG) respectively in cases of 32 neonatal hepatitis , 33 cases of neonatal unconjugated hyperbilirubinemia and 34 cases of breast milk jaundice(BMJ). FBA and CG in acute period of neonatal hepatitis were obviously elevated and decreased gradually in convalescent and recovered period. The difference was significant for each stage as compared with controls. Acute FBA correlated strongly with the course. Both neonatal unconjugated hyperbilirubinemia and BMJ differed significantly from controls in FBA and CG. The results suggested that serum FBA and CG were helpful in Judging the course and state of neonatal hepatitis, and cholestasis might existed in neonatal unconjugated hyperbilirubinemia. |
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| Keywords: | neonate bile acid cholestasis |
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