内源性药物干粉吸入给药的研究进展

目的为探讨内源性药物干粉吸入给药的研究进展,找出其中最适宜的干粉吸入剂的制作工艺和给药方法和剂量。方法从网络最近公开发表的文献综合分析、比较后将适宜的干粉制作工艺和给药方法作了概述。结果内源性药干粉吸入的临床效果、不良反应、病人的感受都比液体气管内滴入给药好,比注射给药更好,相比差异均有显著性。制作工艺以超临界流体技术较好,但因应用时间短尚需继续观察,目前应用较多的喷雾干燥法。结论内源性药物,采用干粉吸入法给药是目前较好的方法,有推广价值。

The study advance of the endogenesis drug xerium inhalation administration

Objective For the discuss endogenous drug xerium inhalation administration study progression, the making technology and medication and dose of the search thereinto optimum xerium inhalant. Methods From the literature synthesize analyse of the meshwork retrieval newly vend, compare since shall condign xerium facture technology and medication progression summarize. Results The endogenous drug xerium inhalationry clinic effect, the instillation administration good inside the adverse reaction sick perception all compare liquid trachea, the compare inject administration very good, compare difference all have significance. The Facture technology with super critical fluid art preferably, the yet because use time no long or want the follow- up survey, the spray-drying process of the now use compare multi. Conclusion The endogenous drug adopt xerium inhalation administration be now comparison good process, have popularization value.