Detection of Human Papillomavirus Type 16 in Sexual Partners of Patients Having Cervical Cancer by Polymerase Chain Reaction |
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| Authors: | Aiko Nakazawa Masaki Inoue Masami Fujita Osamu Tanizawa Akira Akira |
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| Affiliation: | The Department of Obstetrics and Gynecology, Osaka University Medical School, 1-1-50 Fukushima, Fukushima-ku, Osaka 553;The Department of Tumor Virology, Research Institute for Microbial Diseases, 3-1 Yamadaoka, Suita 565 |
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| Abstract: | The polymerase chain reaction (PCR) was employed to detect human papillomavirus (HPV) 16 and 18 in cytological samples from the uterine cervix and in urine samples from the male consorts. HPV 16 was detected in 2 (25%)of 8 males whose wives were positive for HPV 16, while it was detected in only one (7%) of 14 consorts whose wives were negative for HPV 16 and 18. This is the first report of the detection of HPV 16 in urine. Viral detection in urine samples by the PCR method is a non-invasive, convenient and useful tool for large-scale epidemiologic studies and investigations of the mechanism of virus transmission. |
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| Keywords: | Human papillomavirus Sexual partner Polymerase chain reaction Cervical cancer Sexually transmitted disease |
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