磷酸钠口服液用于结肠镜检查肠道准备的临床观察

目的观察评价磷酸钠盐在结肠镜检查前清理肠道的临床效果及其患者耐受性，为我国临床推广使用提供依据及其护理观察经验。方法采用顺序交叉入组对照观察方法，将101例需做结肠镜检查的患者分为试验组50例和对照组51例，实验组采用磷酸钠盐法清理肠道，对照组采用口服蓖麻油＋本院自制的复方电解质溶液法清理肠道。制作统一问卷调查表，记录患者对肠道准备的耐受性和不良反应，以及结肠镜检查医生对肠道清理效果的评价。结果试验组清洁率（96％）高于对照组（92％），但两者比较差异无显著性（P〉0．05）。试验组患者对肠道准备的耐受率（100％）明显高于对照组（82％），两者比较差异有显著性（P〈0．05）。两种肠道准备方法均可出现恶心、呕吐、腹痛、腹胀等副作用，但试验组副作用发生率明显低于对照组（P〈0．05）。结论磷酸钠盐口服液清肠效果满意，耐受性好，副作用低，是一种较为理想的口服清肠剂。

Clinical observation of oral sodium phosphate for colonoscopy preparation

Aim To evaluate the clinical efficacy and tolerance in clinical colonoscopy preparation and to provide evidence for clinical practice and experience. Methods A cross-enrolled trial was performed to observe in 101 patients which were divided into the experimental group（50 cases） and control group（51 eases）. Sodium phosphate was used in experimental group and castor oil plus eleetroeyte lavage solution was used in control group. The patients＇ tolerance, side-effect and cleaning efficacy were recorded. Results The cleaning rate in experimental group（96% ） was higher than that in control group（92% ） ,but there was no difference between these two groups （P 〉0.05）. The tolerance rate in experimental group（ 100% ） was significantly higher than that in control group（82% ） ,P 〈 0.05. The side-effects of nausea, vomiting, abdominal cramps, abdominal fullness could occur in all two groups, but the rate of side-effect was significantly lower in experimental group than that in control group （ P 〈 0.05 ）. Conclusions Oral sodium phosphate is a safe, effective and reliable method for eolonoseopy preparation.