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老年2型糖尿病与轻度认知功能障碍的关系研究
引用本文:李敏,张丽,王敏哲.老年2型糖尿病与轻度认知功能障碍的关系研究[J].中国全科医学,2011,14(14).
作者姓名:李敏  张丽  王敏哲
作者单位:1. 新疆医科大学第六附属医院内分泌科,新疆维吾尔自治区乌鲁木齐市,830000
2. 新疆医科大学第五附属医院内分泌科
摘    要:目的 探讨轻度认知功能障碍(MCI)的影响因素并分析可能影响2型糖尿病(T2DM)患者认知功能的危险因素.方法 选取T2DM患者140例和非T2DM患者102例,将其分为MCI组(126例)与认知功能正常组(NC组,116例).对影响认知功能的因素进行单因素、多因素Logistic回归分析.140例T2DM患者中,合并MCI者94例,认知功能正常者46例,对T2DM认知功能的影响因素进行Logistic回归分析.结果 (1)患有糖尿病、收缩压增高是MCI的危险因素,而文化程度高是MCI的保护因素.(2)血糖控制情况以糖化血红蛋白(HbA1c)表示]、微血管积分是T2DM患者MCI的危险因素,文化程度高是T2DM患者MCI的保护因素(P<0.05).结论 (1)控制血糖和血压有利于改善老年人的认知功能.(2)T2DM是影响MCI发生、发展的重要危险因素.

关 键 词:糖尿病  认知障碍  危险因素

Clinical Research on the Relationship between Type 2 Diabetes and Mild Cognitive Impairment
LI Min,ZHANG Li,WANG Min-zhe.Clinical Research on the Relationship between Type 2 Diabetes and Mild Cognitive Impairment[J].Chinese General Practice,2011,14(14).
Authors:LI Min  ZHANG Li  WANG Min-zhe
Institution:LI Min,ZHANG Li,WANG Min-zhe.Endocrinology Department,the Sixth Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China
Abstract:Objective To investigate influence factors of mild cognitive impairment and analysis risk factors of the diabetic mild cognitive Impairment.Methods(1)140 cases of Type 2 Diabetics and 102 cases of nomal cases were divided into the MCI group and NC group.multiple factor logistic regression analysis were conducted to analysis the impact factors to affect the cognitive impairment.(2)140 cases of T2DM were divided into the MCI group and NC group.Single and multiple factor logistic regression analysis were condu...
Keywords:Diabetes mellitus  Cognition disorders  Risk factors  
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