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散发型戊型肝炎与急性乙肝临床特征比较
引用本文:黄守杰,张雪峰,黄鸿江,姜汉民,王一军,蔡加平,杨昌林,王忠泽,吴婷,朱凤才,张军,夏宁邵. 散发型戊型肝炎与急性乙肝临床特征比较[J]. 中国人兽共患病杂志, 2011, 27(1): 11-13
作者姓名:黄守杰  张雪峰  黄鸿江  姜汉民  王一军  蔡加平  杨昌林  王忠泽  吴婷  朱凤才  张军  夏宁邵
作者单位:黄守杰,HUANG Shou-jie(厦门大学医学院预防医学系,厦门,361005;厦门大学国家传染病诊断试剂与疫苗工程技术研究中心);张雪峰,朱凤才,ZHANG Xue-feng,ZHU Feng-cai(江苏省疾病预防与控制中心);黄鸿江,吴婷,张军,夏宁邵,HUANG Hong-jiang,WU Ting,ZHANG Jun,XIA Ning-shao(厦门大学国家传染病诊断试剂与疫苗工程技术研究中心);姜汉民,王一军,蔡加平,杨昌林,王忠泽,JIANG Han-min,WANG Yi-jun,CAI Jia-ping,YANG Chang-lin,WANG Zhong-ze(江苏省东台市疾病预防与控制中心)
基金项目:国家高技术研究发展计划(863计划)资助项目
摘    要:目的比较散发型急性戊型肝炎与乙肝临床特征。方法分析戊肝和急性乙肝间年龄、性别、肝脏损伤、症状体征以及病程的差异。结果急性肝炎病例中,戊型肝炎最常见(28.0%),急性乙肝次之(9.2%);戊肝平均发病年龄为56.3±13.1岁,急性乙肝为43.0±12.5岁,平均发病年龄戊肝较急性乙肝大(t=4.4723, P<0.0001),均为男性多发;两者常见的临床症状和体征基本相当,但戊肝患者黄疸症状更多见(P<0.05);戊肝病程较急性乙肝长(t=3.7249, P=0.0003);通过年龄性别进行1∶1匹配分析,戊肝比急性乙肝对肝脏的损伤程度严重(t=3.5978, P=0.0019)。结论戊肝多见于中老年,急性乙肝多见于中青年,均为男性多于女性。临床特征比较戊肝较急性乙肝更为严重。

关 键 词:戊型肝炎  急性乙肝  临床特征  

Comparison of clinical features in acute hepatitis E and B
HUANG Shou-jie,ZHANG Xue-feng,HUANG Hong-jiang,JIANG Han-min,WANG Yi-jun,CAI Jia-ping,YANG Chang-lin,WANG Zhong-ze,WU Ting,ZHU Feng-cai,ZHANG Jun,XIA Ning-shao. Comparison of clinical features in acute hepatitis E and B[J]. Chinese Journal of Zoonoses, 2011, 27(1): 11-13
Authors:HUANG Shou-jie  ZHANG Xue-feng  HUANG Hong-jiang  JIANG Han-min  WANG Yi-jun  CAI Jia-ping  YANG Chang-lin  WANG Zhong-ze  WU Ting  ZHU Feng-cai  ZHANG Jun  XIA Ning-shao
Affiliation:(Department of Preventive Medicine,Medical College of Xiamen University,Xiamen 361005,China)
Abstract:In order to compare the clinical features between sporadic hepatitis E and acute hepatitis B,the age,gender,liver injury,clinical symptom and disease course between acute hepatitis E and B detected in active surveillance were analyzed.ThE results showed that Hepatitis E(28.0%) was the most common disease in acute hepatitis,following by acute hepatitis B(9.2%);the average age of onset of hepatitis E(56.3±13.1) was higher than that of acute hepatitis B(43.0 12.5),and the difference was statistically significant(t=4.4723,P0.0001).In the detected cases,male pateint were mone than that of female,there was no difference in clinical symptoms of both hepatitis E and B;except that jaundice in hepatitis E was more common than acute hepatitis B(P0.05);illness course of hepatitis E was longer than that of acute hepatitis B(t=3.7249,P=0.0003);by 1:1 match of age,liver injury in hepatitis E was severer than that in acute hepatitis B(t=3.5978,P=0.0019).Tn conclusin male patinent were mort than that of female,Hepatitis E was common in middle aged people but in young people it was acute hepatitis B.Both hepatitis E and B were more common in men than women.Hepatitis E was severer than acute hepatitis B by comparing the clinical symptoms.
Keywords:hepatitis E  hepatitis B  clinical features
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