| C肽水平与2型糖尿病周围神经病变的关系研究 |
| |
| 引用本文： | 卢曙芳,陈伟宁,朱麒钱.C肽水平与2型糖尿病周围神经病变的关系研究[J].中国全科医学,2011,14(9). |
| |
| 作者姓名： | 卢曙芳 陈伟宁 朱麒钱 |
| |
| 作者单位： | 1. 绍兴文理学院附属医院,浙江省绍兴市,312000
2. 312000浙江省绍兴市人民医院 |
| |
| 摘 要： | 目的 探讨C肽水平变化与糖尿病周围神经病变(DPN)的关系.方法 根据是否合并DPN将152例住院2型糖尿病(T2DM)患者分为T2DM合并DPN组(DPN组,91例)及单纯T2DM组(T2DM组,61例),测定两组患者的身高、体质量、血压、血脂、空腹血糖(FBG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)、空腹C肽、糖负荷2 h C肽、空腹胰岛素(FINS)、糖负荷2 h胰岛素(2 hINS),计算体质指数(BMI).比较两组患者上述指标间的差异,采用Logistic回归分析探讨T2DM合并DPN的危险因素.结果 DPN组患者糖负荷2 h C肽及胰岛素水平、BMI均显著低于T2DM组,而病程、HbA1c水平显著高于T2DM组,差异均有统计学意义(P＜0.05).多元Logistic回归分析显示,T2DM发生DPN与糖负荷2 h C肽水平呈负相关(P=0.000).结论 糖负荷2 h C肽水平与T2DM发生DPN密切相关,而病程与T2DM发生DPN的关系尚需进一步扩大样本量进行研究.
|
| 关 键 词： | 糖尿病 2型 糖尿病神经病变 C肽 |
Relationship between C Peptide Level and Diabetic Peripheral Neuropathy |
| |
| LU Shu-fang,CHEN Wei-ning,ZHU Qi-qian.Relationship between C Peptide Level and Diabetic Peripheral Neuropathy[J].Chinese General Practice,2011,14(9). |
| |
| Authors: | LU Shu-fang CHEN Wei-ning ZHU Qi-qian |
| |
| Institution: | LU Shu-fang,CHEN Wei-ning,ZHU Qi-qian.Affiliated Hospital of Shaoxing Arts and Sciences College,Shaoxing 312000,China |
| |
| Abstract: | Objective To explore the relationship between the levels of C-peptide and diabetic peripheral neuropathy(DPN).Methods A total of 152 T2DM patients were divided into groups T2DM(n=61) and DPN(n=91).Height,weight,blood pressure(BP),lipids,fasting blood glucose(FBG),2 hour postprandial blood glucose(2 hPG),glycosylated hemoglobin(HbA1c),fasting C peptide,2 hour glucose C peptide,fasting insulin(FINS),2 hour glucose load insulin(2 hINS),body mass index(BMI) were determined and compared between 2 groups.Logistic... |
| |
| Keywords: | Diabetes mellitus type 2 Diabetic neuropathies C-peptide |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
