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Cytologic diagnosis of small cell carcinoma of the ovary: A case report with review of the literature
Authors:Parikshaa Gupta  Swathi Jogunoori  Arvind Rajwanshi  Radhika Srinivasan  Nalini Gupta  Vanita Jain  Chandan Krushna Das
Abstract:Small cell carcinoma of the ovary (SCCO) is an exceedingly rare malignant neoplasm. It has been classified into two types: hypercalcemic and pulmonary type, the former being relatively more common. These are highly aggressive neoplasms with rapid down‐hill course and poor disease‐outcome. A high index of clinical suspicion, systematic radiological evaluation, and an early tissue diagnosis are a must for timely patient management and a better outcome. A definitive diagnosis can be established by demonstration of the characteristic morphologic and immunochemical features. We report a case of SCCO of pulmonary type in a peri‐menopausal female, presenting with a large abdomino‐pelvic mass, which was diagnosed by fine needle aspiration cytology (FNAC), by immunocytochemistry on cell‐block. In addition, cytological features of metastatic SCCO, pulmonary type, in the Papanicolaou stained liquid‐based cytology (SurePath) preparation are also presented. The current report highlights the diagnostic utility of FNAC in the diagnosis of such rare gynecological malignancies.
Keywords:cervical cytology  fine needle aspiration cytology  small cell carcinoma ovary  small cell carcinoma ovary, hypercalcemic type  small cell carcinoma ovary, pulmonary type
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