单纯化学治疗及联合西黄胶囊治疗晚期肺腺癌临床分析 |
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引用本文: | 杜凤华,闵旭红.单纯化学治疗及联合西黄胶囊治疗晚期肺腺癌临床分析[J].安徽中医学院学报,2018,37(2):34-36. |
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作者姓名: | 杜凤华 闵旭红 |
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作者单位: | 安徽省胸科医院,安徽 合肥 230031 |
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摘 要: | 目的 探讨单纯化学治疗及联合西黄胶囊治疗晚期肺腺癌的临床疗效及安全性。方法 将62例符合纳入标准的晚期肺腺癌患者随机分为观察组(培美曲塞+卡铂/顺铂+西黄胶囊治疗)和对照组(培美曲塞+卡铂/顺铂治疗),每组30例,观察治疗后两组患者临床症状改善情况、不良反应发生情况以及评估疗效。结果 两组患者临床症状疗效分布比较,差异具有统计学意义(P<0.05);两组患者不良反应比较,差异无统计学意义(P>0.05);观察组的有效率、疾病控制率高于对照组,但差异尚无统计学意义(P>0.05)。结论 使用西黄胶囊辅助抗肿瘤的疗效更佳,临床症状明显改善,且没有增加不良反应。
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关 键 词: | 肺癌 肺腺癌 西黄胶囊 |
Clinical Effect of Chemotherapy Alone or in Combination with Xihuang Capsule in Treatment of Advanced Lung Adenocarcinoma |
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Institution: | Anhui Chest Hospital, Anhui Hefei 230031, China |
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Abstract: | Objective To investigate the clinical effect and safety of chemotherapy alone or in combination with Xihunag Capsule in the treatment of advanced lung adenocarcinoma. Methods A total of 62 patients with advanced lung adenocarcinoma who met the inclusion criteria were randomly divided into observation group with 32 patients (pemetrexed + carboplatin/cisplatin + Xihuang Capsule) and control group with 30 patients (pemetrexed + carboplatin/cisplatin). The two groups were observed in terms of improvement in clinical symptoms after treatment, incidence of adverse events, and treatment outcome. Results There was a significant difference in the distribution of outcomes of clinical symptoms between the two groups (P<0.05). There was no significant difference in the incidence of adverse events between the two groups (P>0.05). The observation group had higher response rate and disease control rate than the control group (P>0.05). Conclusion Xihuang Capsule has a good antitumor effect and can be used during chemotherapy to significantly improve clinical symptoms, and it does not increase the incidence of adverse events. |
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Keywords: | Lung cancer Lung adenocarcinoma Xihuang Capsule |
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