| 草分枝杆菌对SPCA/Ι人肺癌细胞生长抑制作用的研究 |
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| 引用本文： | 朱慕云,吕元文,姜正华,宗文九,郭媛,甘军纪.草分枝杆菌对SPCA/Ι人肺癌细胞生长抑制作用的研究[J].实用临床医药杂志,2001(1). |
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| 作者姓名： | 朱慕云 吕元文 姜正华 宗文九 郭媛 甘军纪 |
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| 作者单位： | 扬州大学临床医学院!扬州，225002，扬州大学临床医学院!扬州，225002，扬州大学临床医学院!扬州，225002，扬州大学临床医学院!扬州，225002，扬州大学临床医学院!扬州，225002，扬州大学畜牧兽医学院!扬州，225001 |
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| 摘 要： | 目的 :探讨草分枝杆菌 (MycobacteriumPhlei)对人肺腺癌细胞系SPCA /Ⅰ的抗增殖效应。 方法 :应用细胞培养和MTT比色法检测不同浓度组的草分枝杆菌对SPCA /Ⅰ人肺腺癌细胞生长的抑制作用 ,波长定于 5 70nm ,测定光密度 (A值 )并计算其抑制率。结果 :不同浓度的草分枝杆菌体外对人肺腺癌细胞株SPCA/Ⅰ均有直接的抑制作用 ,其抑制率与所用药物浓度呈正相关。结论 :草分枝杆菌体外对SPCA/Ⅰ人肺腺癌细胞有直接的抑制作用 ,该结果可能为肿瘤的临床联合治疗提供实验依据。
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| 关 键 词： | 草分枝杆菌 抗增殖效应 肺癌 |
EXPERIMENTAL STUDY OF THE GROWTH SUPPRESSION EFFECTS ON HUMAN LUNG CANCER CELL LINES WITH MYCOBACTERIUM PHLEI |
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| ZHU Mu yun,LU Yuan wen,JIANG Zheng hua,et al.EXPERIMENTAL STUDY OF THE GROWTH SUPPRESSION EFFECTS ON HUMAN LUNG CANCER CELL LINES WITH MYCOBACTERIUM PHLEI[J].Journal of Clinical Medicine in Practice,2001(1). |
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| Authors: | ZHU Mu yun LU Yuan wen JIANG Zheng hua |
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| Abstract: | Objective:To study the activity of the growth suppression effects with Mycobacterium Phlei on SPCA /Ⅰ human lung adenocarcinoma cell.Methods:The suppression effects of lung cancer cell with Mycobacterium Phlei were measured by a tetrazolium-based volorimetric assay (MTT assay),the wave length was set at 570nm,the light density(A) was determined and the rate of mhibition was caculated.Results:Mycobacterium Phlei has the direct growth suppression effects on SPCA /Ⅰ human lung adenocarcinoma cell ,also shows the positive correlations with the concentration of Mycobacterium Phlei.Conclusions:Mycobacterium Phlei has the direct growth suppression effects on SPCA /Ⅰ human lung adenocarcinoma cell.Which might provide experimental evidents to lung cancer therapy. |
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| Keywords: | mycobacterium Phlei growth suppression effects lung cancer |
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