愈带丸质量标准研究

目的：建立愈带丸中当归、木香、黄柏的薄层色谱方法及芍药苷的高效液相含量测定的方法。色谱柱为AgilentC18;流动相为乙腈-0．1％磷酸溶液梯度洗脱；流速为1．0mL·min^-1；检测波长230nm；柱温25℃，芍药苷在0．0678～2．373nag范围内呈良好的线性关系，r=1，平均回收率100．14％，RSD为2．40％（n=6）。该方法操作简便，重复性好，结果准确可靠，适用于该药的质量控制，推荐收入2010年版《中国药典》。

Study on Quality Standard of Yudai Pills

Objective ：To establish the quality standards of Yudai Pills. Radix Angelicae Sinensis, Radix Aucklandiae and Cortex Phel- lodendri were identified by TLC method, and paeonin was determined by HPLC method. Agilent CIS column was used and the column temperature was 25℃. The mobile phase consisted of acetonitfile -0. 1% phosphoric acid aqueous solution using a gradient elution and the flow rate was 1.0 mL · min ^- 1. UV-detection was accomplished at 230 nm. The calibration curve of paeonin was linear （ r = 1 ） in the range of 0. 067 8 -2. 37 3 mg,the mean recovery was 100. 14% with RSD 2. 40% （n =6）. The result showed that the methods were simple, repeatable and accurate and suitable for quality control of Yudai Pills. The proposed standard was supposed to be adopted in Chinese Pharmacopoeia of 2010 Edition.