| 茶多酚抑制AFB_1致大鼠肝癌作用的初步研究 |
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| 引用本文： | 覃国忠,覃柳亮,段小娴,刘明彻,严瑞琪. 茶多酚抑制AFB_1致大鼠肝癌作用的初步研究[J]. 广西医科大学学报, 1990, 0(3) |
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| 作者姓名： | 覃国忠 覃柳亮 段小娴 刘明彻 严瑞琪 |
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| 作者单位： | 广西肿瘤防治研究所，广西肿瘤防治研究所，广西肿瘤防治研究所，广西肿瘤防治研究所，广西肿瘤防治研究所 中山医科大学肿瘤防治中心 |
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| 摘 要： | 应用AFB_1致肝癌作用的短期实验模型,观察绿茶成分茶多酚对AFB_1诱发肝癌前病变酶变灶的影响。结果发现,茶多酚对肝癌前病变大偏差酶变灶、小偏差酶变灶及总酶变灶均有显著的抑制作用。提示茶多酚可能是茶叶防癌的主要有效成分之一。
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| 关 键 词： | 茶多酚 AFB_1 肝癌 酶变灶 |
A PRIMARY STUDY OF THE INHIBITORY EFFECTS OF GREEN TEA POLYPHENOLS ON AFLATOXIN B_1-INDUCED HEPATOCARCINOGENESIS IN RATS |
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| Guangxi Cancer Institute Qin Guozhong,et al. A PRIMARY STUDY OF THE INHIBITORY EFFECTS OF GREEN TEA POLYPHENOLS ON AFLATOXIN B_1-INDUCED HEPATOCARCINOGENESIS IN RATS[J]. Journal of Guangxi Medical University, 1990, 0(3) |
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| Authors: | Guangxi Cancer Institute Qin Guozhong et al |
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| Abstract: | Green tea polyphenols(GTP)were tested for their effects on aflatoxin B_1(AFB_1)-induced hepatocarcinogenesis in rats,using the short term in vivo experimental model.The results showed that GTP had significant inhibitory effects on the development of AFB_1-induced maximally deviated, mimimally deviated and total enzyme-altered foci.Our experimental results suggest that GTP may be the main component of green tea responsible for cancer prevention. |
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| Keywords: | green tea polyphenols AFB_1 hepatocarcinoma enzyme-al tered foci |
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