降钙素、睾酮及甲状旁腺激素与骨质疏松患者骨密度的关系

目的：探讨降钙素、睾酮及甲状旁腺激素与骨质疏松患者骨密度的关系。方法选择确诊老年骨质疏松症患者40例为观察组，选取正常体检者40例为对照组，测定两组不同部位骨密度，并分析降钙素、睾酮及甲状旁腺激素水平的变化。结果观察组第四腰椎、股骨大转子及前臂远端骨密度均显著低于对照组（P＜0.05）。观察组降钙素、睾酮水平均低于对照组（P＜0.05），甲状旁腺激素水平高于对照组（P＜0.05）。结论老年骨质疏松症患者降钙素、睾酮水平降低，甲状旁腺激素升高，可作为临床诊断的指标之一。

The relationship on calcitonin,estosterone and parathyroid hormone with bone mineral density of patients with osteoporosis

Objective To investigate the relationship on calcitonin, estosterone and parathyroid hormone with bone mineral density of patients with osteoporosis. Methods 40 elderly patients with osteoporosis were selected as observa-tion group,40 cases of normal volunteers were selected as control group.Bone mineral density of different parts in two groups were measured,calcitonin,testosterone and parathyroid hormone levels were analyzed. Results Bone mineral den-sity of fourth lumbar vertebra,greater trochanter and distal forearm in observation group was significantly lower than that in control group respectively （P〈0.05）.The calcitonin,testosterone level in observation group was lower than that in con-trol group respectively（P〈0.05）,parathyroid hormone level in observation group was higher than that in control group（P〈0.05）. Conclusion Elderly patients with osteoporosis have lower calcitonin,testosterone level and higher parathyroid hormone,can be used as an indicator of clinical diagnosis.