| 胎盘活性因子体外抗单纯疱疹病毒作用 |
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| 引用本文： | 程丽,陈文凯,诸卫平. 胎盘活性因子体外抗单纯疱疹病毒作用[J]. 武汉大学学报(医学版), 1999, 20(2): 2 |
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| 作者姓名： | 程丽 陈文凯 诸卫平 |
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| 作者单位： | 同济医科大学附属协和医院普外科!武汉430022 |
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| 摘 要： | 目的：探讨胎盘活性因子（ＰＡＦ） 在细胞培养中对单纯疱疹病毒（ＨＳＶ）起抑制作用。方法：运用间接免疫荧光法检测药物抗病毒作用。结果：ＰＡＦ对病毒吸附细胞无干扰作用，而对病毒有直接的杀伤及抑制作用。以抑制浓度为１００ μｇ／ｍｌ，作用时间为８ ｈ 效果最好。结论：该药对细胞无毒无害，无副作用，是较为理想的免疫调节剂。
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| 关 键 词： | 胎盘活性因子 疱疹病毒,人 荧光免疫测定 |
Anti HSV Action of Placental Active Factor in Vitro |
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| Cheng Li,Chen Wenkai,Zhu Weiping,et al. Anti HSV Action of Placental Active Factor in Vitro[J]. Medical Journal of Wuhan University, 1999, 20(2): 2 |
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| Authors: | Cheng Li Chen Wenkai Zhu Weiping et al |
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| Abstract: | Objective:To elucidate inhibitory effect of placental active factor (PAF) on herps simplex virus (HSV) in cell cultures.Methods:The antiviral effect of drug was examined by an indirect immunofluorescence assay.Results:The fact that viruses absorb cells can not be prevented by PAF.This showed that direct killing and inhibitory effect of PAF for HSV is involved.The inhibitory concentraction is 100 μg/ml.The result is best at 8th hour than any other times.Conclusions:This PAF is nontoxic,harmless and produces no side effect in cell culture.The immunomodulator is ideal. |
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| Keywords: | placental active factor herpesvirus hominis fluoroimmunoassay |
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