| 局部注射DBM,BMG修复骨缺损的实验研究 |
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| 引用本文： | 谭祖键,林贵德.局部注射DBM,BMG修复骨缺损的实验研究[J].中华创伤杂志,1994,10(4):171-172. |
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| 作者姓名： | 谭祖键 林贵德 |
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| 作者单位： | 中国人民解放军五三三医院骨科，第三军医大学附属大坪医院骨科 |
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| 摘 要： | 实验选用Ｗｉｓｔａｒ大白鼠尺骨中段截骨造成骨缺损模型，骨缺损长度平均６．１ｍｍ。８１只大白鼠随机分为３组，每组２７只。术后２周各组分别于骨缺损部位注射脱钙骨基质（ＤＢＭ）、骨基质胶（ＢＭＧ）及明胶各５０ｍｇ的生理盐水混悬液。结果表明：ＤＢＭ、ＢＭＧ组注射２周，Ｘ线照片示骨缺损开始修复，ＢＭＧ组１２周完全修复，ＤＢＭ组１６周完全修复。新骨形成较其它报道略为提早。本实验未见免疫排斥反应。
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| 关 键 词： | 脱钙骨基质 骨基质胶 注射 骨缺损 |
An Experimental Study on Local Injection of DBM And BMG in Repairment of Bone Defects |
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| Tan Zu-jian,Nin Gui-de.Dept.of Orthopedics, rd Hospital PLA,Kumming.An Experimental Study on Local Injection of DBM And BMG in Repairment of Bone Defects[J].Chinese Journal of Traumatology,1994,10(4):171-172. |
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| Authors: | Tan Zu-jian Nin Gui-deDeptof Orthopedics rd Hospital PLA Kumming |
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| Institution: | Tan Zu-jian,Nin Gui-de.Dept.of Orthopedics,533 rd Hospital PLA,Kumming 650224 |
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| Abstract: | he
study was carried out by using 81 wistar rats that were divided into 3 groups randomly,each
group containing 27 rats. The experimental model of bone defect was made by cutting off the
milldle part of the ulna. The length of the bone defect was 6. 1mm. Two weeks later,the ulna
defect was injected with 50mg suspension of DBM(DBM group).BMG(BMG group)andgelatin(the
controd group).Two weeks after the injection, the x-ray film showed the bone defect began to
repair in the DBM andBMG groups. The BMG group assumed complete repair in bone defect at
12 week and the DBM group a complete healing processat 16 week.The new bone formation was
earlier than that in other repairts. There was no immunological rejection in the experi- ment. |
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| Keywords: | DBM BMG Injection Bone defect |
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