中国人群血脂流行病学研究25年回顾与展望

血脂异常与心脑血管疾病的发生密切相关。血清总胆固醇增高,特别是低密度脂蛋白胆固醇增高,是冠心病的重要危险因素。而三酰甘油增高、高密度脂蛋白胆固醇降低也可增加冠心病的危险性。我国开展的血脂流行病学研究,提供了不同年代、不同人群的血脂水平、分布特征及血脂异常患病率等宝贵数据,反映了我国人群血脂水平及其影响因素变化的主要特征和趋势。通过这些研究不仅看到我国人群血脂水平存在地区差异、城乡差异和性别差异,同时也看到了我国经济发展和生活方式的改变对人群血脂异常的重要作用和不利影响。进一步证实了我国人群血脂异常在主要心脑血管病发病的作用。

25-Year Retrospect and Forecast of Epidemiology Studies on the Chinese Population's Plasma Lipids

Dyslipidemia is closely related to cardiovascular and cerebrovascular diseases.An increased plasma total cholesterol(TC),especially an increased low-density lipoprotein cholesterol(LDL-C) concentration is an important risk factor for coronary heart disease.Meanwhile,an increased triglyceride(TG) and a decreased high-density lipoprotein cholesterol(HDL-C) concentration can also increase the risk of coronary artery disease.The epidemiological studies on different Chinese populations have provided valuable data about the levels and distribution of plasma lipids and prevalence of dyslipidemia at different periods.The studies also show us the main characteristics,trends and influencing factors of the plasma lipids.The regional disparities,differences between men and women,and differences between urban and rural districts are revealed in the studies,along with the negative effects of economic development and changing lifestyles in China.All these prove that dyslipidemia plays an important role in the Chinese incidence of cardiovascular and cerebrovascular diseases.