| 长春瑞滨联合顺铂治疗晚期乳腺癌43例 |
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| 引用本文： | 冷嘉兴,孙毅,徐珍,周彤,凌扬.长春瑞滨联合顺铂治疗晚期乳腺癌43例[J].肿瘤学杂志,2003,9(6):355-356. |
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| 作者姓名： | 冷嘉兴 孙毅 徐珍 周彤 凌扬 |
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| 作者单位： | 常州市肿瘤医院,江苏,常州,213001 |
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| 摘 要： | 目的]观察长春瑞滨(NVB)为主联合化疗对晚期乳腺癌的疗效和毒副反应。方法]43例均为住院患者,初治12例,复治31例;具体为NVB25mg/m2d1,8;DDP25mg/m2d1~3;q3w重复;至少完成2周期后评价疗效。结果]CR5例(11.6%),PR17例(39.5%),SD16例(37.2%),PD5例(11.6%)。总有效率(RR)51.2%,其中初治12例58.3%,复治31例48.4%;Ⅲ期13例61.5%,Ⅳ期30例42.4%。主要毒副反应:骨髓抑制和恶心、呕吐、脱发,其他反应轻微。结论]NP方案为治疗晚期乳腺癌有效而安全的方案。
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| 关 键 词： | 乳腺肿瘤 药物疗法 长春瑞滨 |
| 文章编号： | 1671-170X(2003)06-0355-02 |
| 修稿时间： | 2003年7月22日 |
Navelbine Combined with Cisplatin in The Treatment for 43Patients with Advanced Breast Cancer |
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| LENG Jia-xing,SUN Yi,XU Zheng,et al..Navelbine Combined with Cisplatin in The Treatment for 43Patients with Advanced Breast Cancer[J].Journal of Oncology,2003,9(6):355-356. |
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| Authors: | LENG Jia-xing SUN Yi XU Zheng |
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| Abstract: | To evaluate the therapeutic effect and toxicitie s of navelbine(NVB)combined with cisplatin regimen in the treatment for advanced b reast cancer.Forty-three cases with advanced breast cancer were verifi ed by pathology.NVB25mg/m 2 iv on day1,day8,DDP25mg/m 2 iv on day1~day3,and repeated every3weeks.Five cases showed complete response and17cases showed partial response.The overall response rate was51.2%. The major toxic effects were myelosuppression,vomitting and alopecia.Conclusion]NVB combined with cisplatin is an effective treatment for the patients with adv anced breast cancer and toxicities of this treatment are tolerated. |
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| Keywords: | bre ast neoplasms drug therapy navelbine |
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