麻附三藤汤加减治疗寒湿痹阻型类风湿性关节炎30例

目的:观察麻附三藤汤加减治疗寒湿痹阻型类风湿性关节炎的临床疗效。方法:将60例寒湿痹阻型类风湿性关节炎患者随机分为对照组和研究组,每组各30例。对照组采用口服来氟米特片、甲氨蝶呤、双氯芬酸钠缓释片进行常规治疗,研究组采用麻附三藤汤加减治疗。比较两组患者的临床疗效,观察两组患者治疗前后关节压痛数、关节肿胀数、晨僵时间及中医证候积分变化情况。结果:对照组有效率为63.3%,研究组有效率为86.7%,两组患者临床疗效比较,差异具有统计学意义(P0.05)。两组患者治疗后关节肿胀数、关节压痛数、晨僵时间均低于治疗前,且研究组低于对照组,差异均有统计学意义(P0.05)。治疗后两组患者中医证候积分均低于治疗前,且研究组低于对照组,差异均有统计学意义(P0.05)。结论:麻附三藤汤加减治疗寒湿痹阻型类风湿性关节炎疗效显著,能有效缓解临床症状与体征,减轻关节疼痛,改善患者生存质量。

Thirty Cases of Rheumatoid Arthritis with Cold-Damp Arthralgia Syndrome Treated with Modified Mafu Santeng Decoction

Objective:To observe the clinical curative effect of Modified Mafu Santeng Decoction (MMFSTD) on rheumatoid arthritis with cold-damp arthralgia syndrome.Methods:Sixty patients with rheumatoid arthritis with cold-damp arthralgia syndrome were randomly divided into the control group and the research group,with 30 cases in each group.The ones in the control group were given routine Western medicine treatment,such as Leflunomide Tahlets;methotrexate Diclofenac Sodium Sustained Release Tablets,while the ones in the research group were treated with MMFSTD.The clinical effects of the two groups were compared.The changes of the number of joint tenderness,the number of joint swelling,the time of morning stiffness and TCM syndrome scores before and after the treatment in the two groups were observed.Results:The effective rate of the control group was 63.3％,while that of the research group was 86.7％,and the difference between the two groups was statistically significant(P ＜ 0.05).After the treatment,the two groups' number of joint swelling,number of joint tenderness,and time of morning stiffness were all lower than those before the treatment,and the research group was lower than the control group,and all the differences were statistically significant(P ＜ 0.05).What's more,their TCM syndrome scores were all all lower than those before the treatment,and the research group was lower than the control group,and all the differences were statistically significant(P ＜ 0.05).Conclusion:MMFSTD has a remarkable clinical curative effect on rheumatoid arthritis with cold-damp arthralgia syndrome,can effectively alleviate the clinical symptoms and signs,relieve joint pain and improve the quality of life of patients.