| 药敏指导下的晚期乳腺癌化疗 |
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| 引用本文： | 宁连胜,侯子正,李丽庆,毛慧生,孙慧,赵文华,王文治,韩来声,赵宝林,张天泽.药敏指导下的晚期乳腺癌化疗[J].中国肿瘤临床,1991(Z1). |
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| 作者姓名： | 宁连胜 侯子正 李丽庆 毛慧生 孙慧 赵文华 王文治 韩来声 赵宝林 张天泽 |
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| 作者单位： | 天津市肿瘤研究所肿瘤医院，天津市肿瘤研究所肿瘤医院，天津市肿瘤研究所肿瘤医院，天津市肿瘤研究所肿瘤医院，天津市肿瘤研究所肿瘤医院，天津市肿瘤研究所肿瘤医院，天津和平区东兴市场卫生院，天津和平区东兴市场卫生院，天津河北区新开河卫生院，天津市肿瘤研究所肿瘤医院 |
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| 摘 要： | 1982年,我们开始用正常小鼠肾包膜下移植方法(SRC)测定抗癌药物的敏感性。1986年应用临床治疗女性晚期乳腺癌。本文报告22例,年龄37～60岁,,除2例外,先前曾接受过放疗、化疗。22例中,单药治疗14例,联合用药8例。按国际通用标准评定疗效。结果,单药组及联合用药组的有效率分别为64％和87.5％,明显优于常用有效单药及联合化疗方案。
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| 关 键 词： | 化疗晚期乳腺癌 肾包膜下移植方法(SRC) 药物敏感性 |
Chemotherapy of Advanced Breast Cancer under Guidance of Chemosensitivity Test (SRC Assay) |
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| Ning Lian-Sheng,Hou Zi-Zheng et al Tianjin Cancer Hospital and Institute,Tianjin.Chemotherapy of Advanced Breast Cancer under Guidance of Chemosensitivity Test (SRC Assay)[J].Chinese Journal of Clinical Oncology,1991(Z1). |
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| Authors: | Ning Lian-Sheng Hou Zi-Zheng Tianjin Cancer Hospital and Institute Tianjin |
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| Abstract: | From Oct. 1986 to Dec. 1987, 24 patients with advanced breast cancer were treated by chemotherapy under the guidance of tumor response to chemotherapeutic agents with a 6-day subrenal capsule (SRC) assay. Among 22 evaluable cases, 14 cases were treated with single drug and 8 cases with combined agents. According to WHO's criterion for evaluating therapeutic effects, response rate of 64% was achieved in single drug group and 87.5% in combined agents group, which were evidently superior to chemotherapy given empirically. |
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| Keywords: | Chemotherapy Chemosensitivity Advanced breast cancer Subrenal capsule assay |
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