Distribution of Helicobacter pylori virulence markers in patients with gastroduodenal diseases in Pakistan |
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| Authors: | Javed Yakoob Shahab Abid Zaigham Abbas Wasim Jafri Zubair Ahmad Rashida Ahmed and Muhammad Islam |
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| Institution: | (1) Department of Medicine, Aga Khan University, Karachi, Pakistan;(2) Department of Pathology, Aga Khan University, Karachi, Pakistan |
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| Abstract: | Background
Helicobacter pylori (H. pylori) infection is known to be associated with a spectrum of gastroduodenal diseases. We studied the association of H. pylori virulence markers cytotoxin-associated gene (cagA) and vacuolating associated cytotoxin gene (vacA) alleles in patients with non ulcer dyspepsia (NUD), gastric ulcer (GU), gastric carcinoma (GC) and duodenal ulcer (DU). |
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