|
|||||
|
|
The effect of maternal and infant factors on cord blood yield |
|
| Authors: | Seyed Hadi Mousavi Saeid Abroun Morteza Zarrabi Mona Ahmadipanah |
| Affiliation: | 1. Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran;2. Department of Hematology, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran;3. Royan Stem Cell Technology Institute, Tehran, Iran |
| Abstract: | Umbilical cord blood (CB) can be used as an alternative hematopoietic stem cell source for transplantation in hematological malignancy and blood disorders. The success of transplantation is highly related to the levels of total nucleated cell and CD34+ cell counts. The evaluation of optimal conditions can decrease the rate of graft rejection due to low cell count and increases the quality of CB units (CBUs) in the blood bank and the success rate of engraftment. To this end, we review the maternal and infant parameters affecting the quality and quantity of CBUs. |
| Keywords: | cord blood bank cryopreservation hematopoietic stem cell stem cell transplantation umbilical cord blood |