甲状腺髓样癌的预后因素分析

目的　评估影响甲状腺髓样癌预后的因素。方法　采用统计学单、多因素分析研究本院初治 5 3例甲状腺髓样癌的预后因素。结果　总的 5年、10年、15年生存率各自为 6 6 %、5 9.9%和 5 3.2 %。单因素分析示 :原发灶累及双侧 ,原发灶 >4cm ,病灶外侵甲状腺包膜 ,无腹泻症状 ,远处转移 ,手术彻底程度影响预后。多因素示 :手术彻底程度是影响甲状腺髓样癌生存的独立预后因素。结论　手术彻底程度是影响甲状腺髓样癌生存的独立预后因素。

The prognostic factors of medullary thyroid carcinoma

Objective To evaluate prognostic factors of medullary thyroid carcinoma. Methods By using univariate analysis and multivariate analysis,the prognostic factors were studied in 53 patients with medullary thyroid carcinoma treated initially at our hospital.Results Overall survival rates of 5 year,10 year and 15 year were 66.0%,59.9% and 53.2% respectively.In univariate analysis, primary site involving bilateral thyroid,diameter >4cm,and invasion of thyroid capsule,distant metastasis, no diarrhea and radical status of operation were significant poor prognostic factors.In multivariate analysis,only radical status of operation remained as an independent prognostic factor.Conclusion Only radical status of operation remains as an independent predictor of survival.