Concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma |
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| Authors: | Claire Geurten Albert Thiry Paul Jamblin Martine Demarche Claire Hoyoux |
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| Affiliation: | 1. Faculty of MedicineUniversity of Liege;2. Department of Anatomopathology, Clinique CHR de la Citadelle, Liège, Belgium;3. Department of Radiology, Clinique CHR de la Citadelle, Liège, Belgium;4. Division of Pediatric surgery, Department of General Surgery, Clinique CHR de la Citadelle, Liège, Belgium;5. Division of Pediatric Hematology‐Oncology, Department of Pediatrics, La Citadelle Regional Hospital, Liège, Belgium |
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| Abstract: | A 10‐year‐old girl with a family history of Hodgkin's lymphoma presented with a 2 month history of cervical lymphadenopathy and weight loss. Biopsy indicated concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma. Such an association is rare, especially so in children, but is not an isolated phenomenon, thereby prompting the question of whether Langerhans cell histiocytosis is a reactive or a neoplastic process. |
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| Keywords: | Hodgkin's lymphoma Langerhans cell histiocytosis neoplasm pediatric synchronous |
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