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Membranous nephropathy presenting with nephrotic syndrome in a child with thalassemia major
Authors:Sevgi Yavuz  Ali Anarat  Aysun Karabay Bayazıt  Barbaros Şahin Karagun  Sema Yılmaz  Yurdanur Kılınc  Gulfiliz Gonlusen  Yurdun Kuyucu
Affiliation:1. Division of Pediatric Nephrology, Cukurova University School of Medicine, Adana, Turkey;2. Division of Pediatric Haematology, Cukurova University School of Medicine, Adana, Turkey;3. Division of Pathology, Cukurova University School of Medicine, Adana, Turkey;4. Histology and Embryology, Cukurova University School of Medicine, Adana, Turkey
Abstract:Few data on the renal effects of thalassemia syndrome are available in the literature. Recent clinical studies identified proximal tubular damage and glomerular filtration abnormalities in thalassemia. Iron‐chelating agents might be nephrotoxic as well, but proven glomerular injury, either due to anemia or chelating therapy, has not previously been demonstrated in thalassemia patients. Here, we report the first thalassemia patient presenting with nephrotic syndrome to be diagnosed with membranous nephropathy in the literature.
Keywords:iron chelator  membranous nephropathy  nephrotic syndrome  proteinuria  thalassemia
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