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大疱性类天疱疮合并原发性腹膜后弥漫大B细胞淋巴瘤1例
引用本文:田珊,李文海,陈周.大疱性类天疱疮合并原发性腹膜后弥漫大B细胞淋巴瘤1例[J].中国皮肤性病学杂志,2012,26(7):633-634,638.
作者姓名:田珊  李文海  陈周
作者单位:北京大学人民医院皮肤科,北京,100044
摘    要:患者男,77岁。躯干、四肢反复红斑、水疱1年余,加重10d,确诊为大疱性类天疱疮。患者发病4年后体检时发现腹膜后肿物,外科手术切除肿物后组织病理显示淋巴样细胞弥漫性浸润,免疫组化示CD20(+),PAX-5(+),Bcl-6(灶+),MUM-1(+),Ki-67(90%+)。诊断:原发性腹膜后弥漫大B细胞淋巴瘤。

关 键 词:类天疱疮  淋巴瘤  大B细胞  腹膜后

Bullous Pemphigoid with Diffuse Large B-cell Lymphoma Primarily Presented in the Retroperitoneum
TIAN Shan , LI Wen-hai , CHEN Zhou.Bullous Pemphigoid with Diffuse Large B-cell Lymphoma Primarily Presented in the Retroperitoneum[J].The Chinese Journal of Dermatovenereology,2012,26(7):633-634,638.
Authors:TIAN Shan  LI Wen-hai  CHEN Zhou
Institution:(Department of Dermatology,People’s Hospital of Peking University,Beijing 100044,China)
Abstract:A 77-year-old male presented with recurrent erythema,blisters and bullae on his body more than one year before,and was diagnosed with bullous pemphigoid(BP).Four years later MRI examination showed a retroperitoneal mass.Histopathologic findings showed a dense diffuse infiltration of lymphatic cells.Immunohistochemical staining showed CD20,PAX-5,Bcl-6,MUM-1,Ki-67 were positive.The final diagnosis is diffuse large B-cell lymphoma primarily presenting in the retroperitoneum.
Keywords:Pemphigoid  Lymphoma  Large B-cell  Retroperitoneum
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