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鼻咽癌的多层螺旋CT灌注成像
引用本文:周作福,吴健,韩明其,刘荣强,陈著声,黄洪磊,林碧金,刘振华. 鼻咽癌的多层螺旋CT灌注成像[J]. 临床耳鼻咽喉头颈外科杂志, 2008, 22(4): 150-152
作者姓名:周作福  吴健  韩明其  刘荣强  陈著声  黄洪磊  林碧金  刘振华
作者单位:南平市医学影像研究所,南平市第一医院放射影像科,福建南平,353000;南平市第一医院耳鼻咽喉科;南平市第一医院病理科;南平市第一医院放疗科
基金项目:福建省教育厅B类科研项目
摘    要:目的:研究鼻咽癌多层螺旋CT各灌注参数的改变和良恶性肿瘤的鉴别诊断.方法:30例鼻咽癌患者行鼻咽血流的CT灌注扫描,30例鼻咽癌患者中有25例行放疗后复查,其中复查时行灌注扫描6例.应用去卷积算法模式计算相应病变区域的血流量(BF)、血容量(BV)、平均通过时间(MTT)和毛细血管通透性(PS).根据不同肿瘤的相关参数图来评价鼻咽癌血流动力学状态.结果:30例鼻咽癌患者BF、BV和PS明显高于肿瘤放疗后组织及正常鼻咽组织,而MTT值差异无统计学意义,结论:灌注参数BF、BV和PS可有效地评价鼻咽癌的血流状态,在鼻咽良恶性病变的鉴别诊断及预后的判断上有重要的临床参考价值.

关 键 词:血流灌注  鼻咽肿瘤  体层摄影术  螺旋计算机
文章编号:1001-1781(2008)04-0150-03
修稿时间:2006-02-27

MSCT perfusion analysis of nasopharyngeal cancer
ZHOU Zuofu,WU Jian,HAN Mingqi,LIU Rongqiang,CHEN Zhusheng,HUANG Honglei,LIN Bijin,LIU Zhenhua. MSCT perfusion analysis of nasopharyngeal cancer[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2008, 22(4): 150-152
Authors:ZHOU Zuofu  WU Jian  HAN Mingqi  LIU Rongqiang  CHEN Zhusheng  HUANG Honglei  LIN Bijin  LIU Zhenhua
Abstract:Objective:To study MSCT perfusion imaging of nasopharyngeal cancer and its differentiated diagnosis.Method: Thirty cases with nasopharyngeal cancer performed multi-detector CT perfusion examination.Among them,there were 6 cases of 25 post-radiotherapy patients performed perfusion imaging with CT scan.Nasopharynx perfusion parameters include blood flow(BF),blood volume(BV),mean transit time(MTT) and permeability surface(PS).Result:Compared with normal region of nasopharynx,BF,BV and PS in nasopharyngeal cancer increased significantly,while MTT has not significant difference between these two areas.Conclusion:Nasopharynx perfusion parameters(BF,BV and PS) measured with CT were significantly altered in nasopharyngeal cancer.There was important appliance value in differentiated diagnosis of nasopharyngeal malignant neoplasms and evaluation of outcome of radiotherapy of nasopharyngeal cancer.
Keywords:Flow perfusion  Nasopharyngeal neoplasms  Tomography  spiral computed
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