2012—2020年泰达国际心血管病医院心血管疾病患者血流感染病原菌分布和耐药性分析

目的 分析泰达国际心血管病医院心血管疾病患者发生血流感染的病原菌分布及耐药特征,为临床合理应用抗菌药物提供依据.方法 对2012年1月—2020年12月泰达国际心血管病医院血流感染病原菌的分布及耐药性进行回顾性分析.结果 共检出病原菌234株,其中革兰阴性菌133株,构成比为56.8％,主要为大肠埃希菌、肺炎克雷伯菌和...

Distribution and drug resistance of bloodstream infection pathogens in cardiovascular patients in TEDA International Cardiovascular Hospital from 2012 to 2020

Objective To investigate the distribution and drug resistance of bloodstream infection pathogens in cardiovascular patients in TEDA International Cardiovascular Hospital, and to provide evidence for rational use of antibiotics.Methods The distribution and drug resistance of bloodstream infection pathogens in TEDA International Cardiovascular Hospital were retrospectively analyzed from January 2012 to December 2020.Results Total 234 strains of bloodstream infection pathogens were isolated. Gram-negative bacteria (133 strains) accounted for 56.8%, and main of them were Escherichia coli, Klebsiella pneumonia, and Enterobacter cloacae. Gram-positive bacteria were 95 strains (40.6%), and main of them were coagulase negative Staphylococcus, Viridans streptococcus, and Staphylococcus aureus. Fungi were 6 strains, accounting for 2.6%. Escherichia coli, Klebsiella pneumonia, and Enterobacter cloacae were highly sensitive to carbapenems and amikacin. Among Staphylococcus, the detection rate of methicillin resistant coagulase negative Staphylococcus was higher than that of Staphylococcus aureus. No Gram-positive bacteria was resistant to linezolid, vancomycin, and teicopalnin.Conclusions Gram-negative bacteria are the main pathogens of bloodstream infection in cardiovascular patients in TEDA International Cardiovascular Hospital. It is necessary to strengthen surveillance of drug resistance of pathogens in bloodstream infection, in order to provide evidence for clinical doctors to use drugs empirically.