重复经颅磁刺激联合动作观察疗法对脑卒中患者运动及认知功能恢复的影响

目的:观察事件相关电位(ERP)指导下重复经颅磁刺激(rTMS)联合动作观察疗法(AOT)对脑卒中恢复期患者认知功能及运动功能的影响。方法:采用随机数字表法将90例脑卒中恢复期患者分为对照组、rTMS组及观察组，每组30例。对照组给予常规康复干预(包括腰部、上肢、下肢、平衡、步行、记忆、注意力、定向力、空间知觉及执行能...

Combining transcranial magnetic stimulation with action observation therapy better improves the neurological functioning of stroke survivors

Objective To observe any effect of combining repetitive transcranial magnetic stimulation(rTMS)under the guidance of event related potentials(ERPs)with action observation therapy(AOT)on the cognitive and motor functioning of stroke survivors in the recovery period.Methods Ninety stroke survivors were randomly divided into a control group,an rTMS group and an rTMS+AOT group,each of 30.All three groups were given conventional rehabilitation treatment(including the training of waist,upper and lower limb function,balance,walking,memory,attention,orientation,spatial perception and executive ability).The rTMS group also received one session of ERP-based rTMS daily five times a week.The rTMS+AOT group was given the same rTMS combined with AOT twice a day,five times a week.Before and after 4 weeks of treatment,the Mini-mental State Examination(MMSE),the Montreal Cognitive Assessment Scale(MOCA),the Fugl-Meyer assessment scale(FMA),the Berg Balance Scale(BBS)and the modified Barthel index(MBI)were used to evaluate each subject′s cognitive and motor ability and their skill in the activities of daily living.Results After the treatment,the average MMSE,MOCA,FMA,BBS and MBI scores of all groups had improved significantly,but the average MMSE,MOCA,upper limb FMA and MBI scores of the rTMS group were then significantly higher than the control group′s averages.And the average scores of the rTMS+AOT group were significantly better than those of the other two groups.Conclusion Combining rTMS guided by ERPs with AOT can effectively improve the cognitive functioning,motor control and balance of stroke survivors,and improve their ability in the activities of daily living.