抗菌药物使用强度影响因子的概念及应用

目的：首次提出了抗菌药物强度影响因子（DIF）的概念，并将其应用于临床抗菌药物使用强度控制管理。方法：通过对临床科室抗菌药物使用频度（DDDs）和同期收治患者人天数（PDi）的数学分析，引入抗菌药物强度影响因子的概念，模拟计算各临床科室对全院抗菌药物使用强度影响因子的大小，并将其作为指标替代原有的药物固定分配方法。结果与结论：抗菌药物强度影响因子代表临床科室对全院抗菌药物使用强度的贡献，数值越高贡献越大。结果还表明，抗菌药物强度影响因子更能够公平地反映各临床科室的抗菌药物使用情况，方便医疗管理人员利用该因子对全院各科室抗菌药物使用情况进行指标管理。

Study on the Concept of Antibiotics Density Impact Factor and Its Application

Objective: To introduce a novel concept of antibiotics density impact factor (DIF) into the control of clinical antibiotics use density. Methods: Through mathematic analysis of the frequency of antibiotics use and the addup of days and patients in each clinical department in the same period, the concept of DFI was introduced and applied to replace the fixed allocation method. Results and Conclusion: DFI can represent departmental contribution to hospital antibiotic use intensity impartially, and provide a new index for hospital management on antibiotics use.