盐藻提取物对尘肺病人抗氧化及细胞免疫功能影响的研究

本文观察了盐藻提取物（ＥＤＳ）对尘肺病人抗氧化和细胞免疫功能的影响。本研究结果提示，ＥＤＳ是一种具有抗氧化、提高免疫功能安全有效的药物，值得在尘肺防治中进一步研究。

Effect fo Extracts of Dunaliella salina(EDS)on Antioxidation and Cellular ImmuneFunction in Patients with Pneumoconiosis

he effect of EDS on antioxidation and cel-lular immune function in patients with pneumo-coniosis who took EDS capsules(15mg each,twice adav)for 30 days was observed in thestudy. The results showed that while serum be-ta-carotene and vitamin A levels increased,blood lipid peroxides(LPO) content markedlydecreased(P<0.01),and the activities of su-peroxide dismutase(SOD)and glutathione per-oxidase(GSH-Px) were significantly increased(P<0.01)than those before administration ofEDS.Cellular immune functions,such as the ac-tivity of tumor necrosis factor(TNF)and lym-phocyte transformation rate(LCTR) improved,that was TNF activity increased(P<0.01 )andLCTR raised(P<0.05 ).It was suggested thatwas effective in improving antioxidation andimmunologic functions of pneumoconiosis pa-tients and was safe at the dose tested.and thatit is worthy to do further study on the action ofthis drug in prevention and treatment of pneu-moconiosis.