持续气道正压通气对合并嗜睡的轻度OSAHS患者的疗效分析

目的:评估持续气道正压通气(continuous positive airway pressure,CPAP)对合并嗜睡的轻度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者的症状和生活质量的影响。方法:纳入轻度OSAHS患者74例,以Epworth嗜睡量表(Epworth sleepiness scale,ESS)进行嗜睡评估,ESS≥10分为嗜睡。伴嗜睡者行CPAP治疗,ESS10分者行健康教育治疗。以Quebec睡眠问卷(Quebec sleep questionnaire,QSQ)进行生活质量评估。8周后对所有患者进行随访。结果:CPAP治疗后,轻度OSAHS患者ESS评分明显下降(P0.01),而QSQ评分显著升高(P0.01),说明CPAP治疗能改善轻度OSAHS患者的嗜睡情况和生活质量。结论:轻度OSAHS患者合并有不同程度的嗜睡,并造成生活质量的下降;CPAP能改善轻度OSAHS患者的嗜睡症状及生活质量。

Evaluation of Continuous positive airway pressure on OSAHS patients accompanied with somnolence

Obstructive sleep apnea hypopnea syndrome (OSAHS)is prevalent and threaten a lot. In present, there exists dispute about the scientific therapeutic manners in mild OSAHS patients. To evaluating different therapeutic manners against the life quality of mild OSAHS patients, our study recruited 74 diagnosed mild OSAHS patients from sleep center of Zhongshan Hospital. Epworth sleepiness scale (ESS) was used to evaluate the degree of somnolence. The ESS score of patients more than ten was designated as somnolence, and continue positive airway pressure (CPAP) was conducted. The ESS score of patients less than ten was designated as non-somnolence, and health education was conducted. Quebec sleep questionnaire (QSQ) was adopted to evaluate the quality of life. All patients was followed up for eight weeks. Results showed that mild OSAHS patients were accompanied with different degree of somnolence and life quality decrease. CPAP could obviously increase the quality of life and alleviate somnolence in mild OSAHS patients. In conclusion, CPAP is a potential effective therapeutic way of mild OSASH.